Ghana: BLIS (UG3/Pilot)

Iron supplementation and nutritional counselling interventions to improve availability and safety of blood in Ghana
SHORT TITLE: Bloodsafe Ghana—Iron and Nutritional Counseling Strategy Pilot Study (BLIS)

A feasibility and acceptability pilot trial of iron supplementation to increase blood donation among blood donors deferred for iron deficiency (ID) and iron deficiency anaemia (IDA) within the catchment areas of the Southern Zonal Blood Centre. The results of the pilot study will inform the design of a larger pragmatic randomized controlled trial to assess the effectiveness of iron supplementation compared to control to increase blood donation success among blood donors deferred for iron deficiency. The pilot study has 2 components: 1) a cross-sectional assessment designed to estimate the prevalence of anaemia leading to donor deferral, the prevalence of ID and the prevalence of IDA among first-time donors, and 2) a longitudinal 2-arm parallel groups trial among first-time voluntary donors that compares haemoglobin levels at 4 months among those with ID or IDA who receive iron supplementation to those without ID or IDA who do not receive iron supplementation. The primary outcome will be haemoglobin levels at 4 months.
Principal Investigators: Dr. Yvonne Dei Adomakoh & Dr. Lucy Asamoah-Akuoko identifier: NCT04949165